Ukrainian company BULOVA, specializing in the production of BULOVA sublimation dryers of the same name, and lyophilized products – Nutricets, produces one of the most expensive and rare in pharmaceuticals and nutrients of substances – Apilarnil.

Apilarnil is actually a homogenate of drone brood (known as apilarnil or less apistimulus) is a product of beekeeping, obtained by collecting drone larvae (male honey bees) from 6-10 day-old drone cells. Apilarnil, which can be defined as the male equivalent of breast milk, obtained from drone brood, and then sublimed (or lyophilized).
Apilaprnil is opened by Romanian apitherapist Nicolas Iliesu, and for the first time plotted in Romania, Today the most popular component of nutrition, medicines and dietary supplements all over the world.
Collection and processing of Apilarnil is exclusively manual work: Getting larvae from hives on a bee farm can be easier before closing the beehive, for closed combs with brood, it is recommended to freeze the combs (at -20°C) or in liquid nitrogen (at -196°C), before proceeding to manual division. A quick and less time-consuming method is to remove the larva and squeeze the unfrozen or thawed combs over a sieve and let the cell mass pass through the sieve. However, such biological mass of drone larva cells must be frozen, because animal protein oxidizes very quickly. Cutting drone larvae from the hive is associated with a loss of biological properties in a very short time. It is important to process the resulting seed within an hour or to protect it from loss of beneficial properties by freezing, canning with honey, precipitation on an adsorbent or lyophilization.
Thanks to the technologies of rapid freezing of raw materials and lyophilization, the product is preserved at low temperatures male honey bee hormones - the main mechanism of action of Nutriceftik Apilarnil, peptides and enzymes!
The Sole trader Bila will use the technological method of quick freezing and lyophilization. Lyophilization – the most expensive method of drying substances in the world! The product is pre-frozen and acquires the state of a dry substance bypassing the liquid state, the drying process is carried out at negative temperatures (without heating). Complex drying equipment is used for lyophilization – Bulova sublimation dryers. During freeze-drying, all substances are preserved in the product, vitamins and trace elements and cell and peptide bond integrity. The freeze-dried product fully corresponds to the fresh product, only the most concentrated due to shrinkage. Sublimation drying is used for the most valuable and expensive materials! (www.dry.in.ua)



The company carries out a full production cycle “apiary – capsule” from collecting drone larvae in own beehives to packaging lyophilized Apilarnil in a capsule.

Finished product – Apilarnil natural lyophilized has product purity 99,5%
-99,5% – a cell of a 7-8-day-old larva of a bee drone,
-0,5% - beekeeping products, which cannot be filtered: honey, Perga, wax. This is confirmed by the international certificate of analysis of the French laboratory ANALYTICE. Analyzes of Apilarnil are carried out only by the method of chromatography.
Like royal jelly, fresh raw apilarnil is two-thirds water. The rest contains protein, Carbohydrates, lipids (jury), 19 different amino acids, except for betacarotene and choline, vitamins A, Well, B2, B2, B6 and minerals (calcium, phosphorus, sodium, potassium and magnesium) and trace elements.
Apilarnil contains a complex of biologically active substances, which cause a number of its pharmacological effects: immunotropic, adaptogenic, anabolic, actoprotective action.
Steroid hormones (androgynous), amino acids, enzymes, trace elements, B vitamins, vitamins A, D cause an anabolic effect.
The presence of a complex of biologically active substances: Carbohydrates, amino acids (glycine, methionine, glutamic acid), of hormones characterizes the actoprotective effect, improvement of human brain activity when using drugs based on Apilarnil. Besides, The value of Apilarnil is also determined by the extremely high content of vitamins A and D. This circumstance may be the basis for the use of Apilarnil in baby food.
But it is not about vitamins and trace elements at all - nthe highest and unique value of Apilarnil in hormones! Essentially Apilarnil – androgen rich sex hormones (as it is the cellular material of the larva a male honey bee – drone) , such as testosterone, prolactin, progesterone and estradiol, used in treatment:
♂ Androgen deficiency syndrome,
♂ To increase libido,
♂ Improvement of erection,
♂ Increase in sperm volume,
♂ Normalization of puberty in adolescence,
♂ Treatment of erectile dysfunction (normalizer of potency and erection).
Precisely because of high hormonal activity – Apilarnil is a powerful immunomodulator, for example: affecting the adaptive immune system Apilarnil has a high antihistaminic effect (anti-allergic) action, suppresses allergies and hypersensitivity of the immune system to allergens.
The Bila company develops and manufactures its own nutraceuticals based on Apilarnil for blood and circulatory system purification, immunomodulators. Based on snail mucus and apilarnil for the treatment of autoimmune diseases of the digestive tract: Crohn's disease, Nonspecific ulcerative colitis and arthritis.
Ukraine is a powerful producer and exporter of natural honey and honey products to Europe, despite the very short honey collection season. Ukrainian high-tech honey product Apilarnil is appreciated in the international market of nutraceuticals and conquers new international pharmaceutical markets, healthy food and cosmetology.
Of course, the cost of such a product is interesting…
Export price of Lyophilized Apilarnil Bulova 1 Euro for 1 gram. Given the high purity of the substance. This is the average value of the substance on international markets.
The high cost of the product is due to the complex production technology, exclusively manual labor at all stages and natural limitations – natural features of reproduction of male bee larvae by bees. Their seeding is extremely low relative to the seeding of worker bee larvae and the main product – honey.
1 gram is how much? The product is very light and hygroscopic, its processing is possible only in a laminar box with a humidity of no more than 5%, this is the international moisture standard for freeze-dried products!
1 gram of lyophilized natural apilarnil, this is a teaspoon without a hill or two large capsules of medium compact size 00.
In its pure form, lyophilized highly concentrated Apilarnil is not used – it is usually a component of natural nutraceuticals, cosmetics and medicines.
According to the materials www.apilarnil.one




